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Scirj Volume V, Issue VII, July 2017 Edition ISSN: 2201-2796 DETERMINATION OF ANTICANDIDAL AND ANTIOXIDANT POTENTIAL OF BLACKBERRY (Rubus fruticosus) FRUIT AND LEAVES EXTRACTS Demet YİĞİT Abstract: : In the present study, water and methanol extracts of blackberry (Rubus fruticosus) were studied for antioxidant and anticandidal properties. The antioxidant properties of fruits and leaves were evaluated by determining radical scavenging power, lipid peroxidation inhibition activity and total phenol content measured with 1,1-diphenyl-2-picrylhydrazyl (DPPH) test, the thiocyanate method and the Folin method, respectively. Both water and methanol extracts have antioxidant potential. The water and methanol extracts of both fruits and leaves have antioxidant potential, ranging from 50.7 % to 64.4 %. Anticandidal activities of above extracts were also tested against clinical isolates of human pathogenic strains belonging 5 yeast species, Candida albicans, Candida glabrata, Candida parapsilosis, Candida krusei and Candida tropicalis by disk-diffusion method. The minimal inhibition concentration (MIC) value of each active extracts was also determined. The most effective antibacterial activity was expressed by methanol extract of blackberry leaves against with 15mm inhibition zone and 0.312 mg/ml MIC value. Reference this Paper: DETERMINATION OF ANTICANDIDAL AND ANTIOXIDANT POTENTIAL OF BLACKBERRY (Rubus fruticosus) FRUIT AND LEAVES EXTRACTS by Demet YİĞİT published at: "Scientific Research Journal (Scirj), Volume V, Issue VII, July 2017 Edition, Page 33-40 ". Search Terms: Blackberry (Rubus fruticosus), Anticandidal activity, Antioxidat activity [Read Research Paper] [Full Screen] |
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